Tier 1 Canada Research Chair

RESEARCH INTERESTS: Study of innate immunity to viral infections and cancer, experimental models of human specific diseases

Medicine, Respirology; Pathology and Molecular Medicine, McMaster Immunology Research Centre

RESEARCH INTERESTS: The Ask lab is studying a molecular pathway termed the unfolded protein response (UPR) that is activated when proteins are not folded correctly in the endoplasmic reticulum (ER).

RESEARCH INTERESTS: Immunosenescence, macrophage biology, macrophage receptor expression, scavenger receptor and phagocytic receptor function and signalling, aging and immunity, innate immunity & host defence, bacterial colonization and infections (e.g. Streptococcus pneumoniae), animal models of pneumonia and post-influenza pneumonia, microbiome of the upper respiratory tract, pathogen, commensals of the upper respiratory tract

RESEARCH INTERESTS: Immunology, Oncology, Translational Research, Genetic Engineering, Immunoassays/Immune Monitoring, First-in-human clinical trials

RESEARCH INTERESTS: HIV, Tuberculosis, Humanized mice, immunology, vaccines, animal models of disease.

Canada Research Chair in Respiratory Mucosal Immunology (Tier 2)

RESEARCH INTERESTS: Respiratory mucosal immunology, environmental exposures, asthma, chronic obstructive pulmonary disease, cystic fibrosis, airway epithelial cells, ATP Binding Cassette (ABC) Transporters commercialization of research, science communication.

RESEARCH INTERESTS: Allergy, particularly food allergy, mucosal immunity

RESEARCH INTERESTS: Mucosal Immunity to HIV & sexually transmitted infections

RESEARCH INTERESTS: Asthma/allergy, rheumatoid arthritis, scleroderma, and graft versus host disease

RESEARCH INTERESTS: Host-virus interactions and viral therapeutics for cancer

RESEARCH INTERESTS: Manufacturing of adenoviral vectors for pre-clinical and clinical applications

RESEARCH INTERESTS: Pandemics, influenza virus, coronavirus, vaccines, antivirals, virus/host interactions, neurodegenerative diseases, B cells, antibodies

RESEARCH INTERESTS: Viral immunity, virus-host interactions in humans and bats, oncolytic viruses, cancer immunotherapy

RESEARCH INTERESTS: Cytokines in chronic inflammatory diseases, cancer microenvironment, fibroblast phenotypes, histopathology, IHC and in situ hybridization in FFPE tissue, animal models

RESEARCH INTERESTS: Chemical Immunomodulatory approaches to combat cancer, multivalent metastatic cell targeting oligomers, covalent re-engineering of immunological machinery and the cancer cell surface

RESEARCH INTERESTS: How environmental and infectious agents, alone or in combination, influence innate and adaptive immune responses in the respiratory tract and the contribution of these changes to the pathogenesis of respiratory disorders such as chronic obstructive pulmonary disease (COPD) and asthma.

RESEARCH INTERESTS: Tumor immunity, cancer vaccines, adoptive T cell therapy, oncolytic viruses

RESEARCH INTERESTS: Anti-microbial mucosal immunity and tuberculosis vaccine development