Jordana group featured by the Allergen Network

A recent publication in the Journal of Clinical Immunology (“The IgE memory reservoir in food allergy”) led by Dr. Rodrigo Jiménez-Saiz in the Jordana lab has garnered great attention and was featured by the Allergen Network. As mentioned in the article, although previous research has shown that “upon re-encountering a food allergen, memory IgE cells become activated and replenish the cells that produce IgE antibodies…no one has been able to decipher how the IgE memory works”. However, in their recent work, the Jordana lab has provided insight into this matter and their findings suggest that “IgG1 memory B cell subsets are the true reservoir of allergen-specific memory, which represents a considerable shift from previous thinking”.

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